Kingherbs offer China Cytisine | Global Trade leader ecrobot

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Kingherbs offer China Cytisine

Posting date : Feb 20, 2013

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Synonyms: Baptitoxine; Sophorine; Ulexine. CAS No.: 485-35-8 Molecular Formula: C11H14N2O Molecular Weight: 190.24 Botanical Source: Seed of Sophora alopecuroides L. and the whole herb of Thermopsis lanceolate. Appearance: White or slightly yellowish crystalline powder Assay: 98%, 99%HPLC Melting Point: 152-153°C Vapour Pressure: 4.95E-07mmHg at 25°C Extract Solvents: Ethanol & Water Description: Cytisine is a chemical found naturally in plants from the Faboideae family e.g. Laburnum, Cytisus, Genista and Sophora. KINGHERBS’s cytisine is from Sophora. Cytisine, also known as baphitoxine and sophorine, is a pyridine-like alkaloid. In medical use, it improves the rate of smoking cessation. It is less effective but much cheaper (≥$6 for a course of treatment) than similar products. Its structure is similar to nicotine and has similar pharmacological effects. In large doses, it can interfere with breathing and cause death. Function: Cytisine is a nicotinic acetylcholine receptor agonist, and as a pharmaceutical preparation it is available for the treatment of nicotinism. That is, Cytisine substance has a mechanism of action similar to the effect of nicotine, but with rather low toxicity. It can substitute nicotine substance, which shortens the period of interaction of nicotine with the respective receptors and hence leads to a gradual reduction and elimination of existing psychic nicotine dependence in smokers. Cytisine derivative varenicline was approved in 2006 as a smoking cessation drug. A 2006 literature review concludes that while trials performed with cytisine itself are mostly of poor quality, there is some evidence that cytisine may be prescribed to aid in smoking cessation. Caution: Cytisine is a pyridine-like alkaloid that can be toxic in high doses. Pharmacologically it exhibits similar effects to nicotione due to structural similarity of the two molecules. In large doses it can interfere with respiration and become fatal. Availability: 50kgs monthly. Packing: Packed in fiber drum, LDPE bag and aluminum-coated plastic bag inside. Net weight:1kg/bag. 25bags per fiber drum. Storage: Keep tightly sealed, store away from moisture, strong heat and direct sunlight. Shelf Life:3 years if sealed and stored in the recommended conditions