Water-soluble Black Pepper Extract

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Water-soluble Black Pepper Extract
Posting date : Nov 27, 2010
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Biochemical basis of enhanced drug bioavailability by piperine : evidence that piperine is a potent inhibitor of drug metabolism. Technical Data Plant Source : Black Pepper Main Ingredient : Piperine Specification : 3.5%(HPLC) Character : It dissolves water completely and has a strong spicy piperine of brown powder. About piperine Piperine is the alkaloid responsible for the pungency of black pepper, along with chavicine (an isomer of piperine). Piperine is often added to prepared food to enhance aroma and Promote drug absorption, and improve the effectiveness of the drug function. In clinical practice, it can induce calm (sedative effect) or to induce sleep (hypnotic effect), and used to make anticonvulsant, antidepressant, and muscle relaxation drug. Function Piperine has also been found to inhibit human CYP3A4 and P-glycoprotein, enzymes important for the metabolism and transport of xenobiotics and in animal studies, piperine also inhibited other enzymes important in drug metabolism. By inhibiting drug metabolism, piperine may increase the bioavailability of various compounds. Notably, piperine may enhance bioavailability of curcumin by 2000% in humans.

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