Probenecid;4-[(Dipropylamino)sulfonyl]benzoic acid

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Probenecid;4-[(Dipropylamino)sulfonyl]benzoic acid
Posting date : Apr 28, 2010
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30-
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Probenecid;4-[(Dipropylamino)sulfonyl]benzoic acid drug name : carboxymethyl benzene Foreign Name : Probenecid, Apurina, BENEMID, Brobecid, Ethamide, Probalan, Proben Molecular formula : C13H19NO4S MW : No. 57-1 258.36 CAS-66-9 nature : 194-196 ° C melting point. Water-soluble <0.1 g/100 mL at 20 ° C. "nature : the white crystalline powder. 194-196 ° C melting point. Soluble acetone, ethanol or slightly soluble in chloroform, almost insoluble in water. Soluble dilute sodium hydroxide solution, the acid almost insoluble. No bad taste, slightly bitter flavor. " purposes : anti-gout drug. The materials for organic acids, soluble strong, since the tubular secretion from shy and easy to absorb. "1. for the treatment of chronic gout. 2. Competitive inhibition can be weak organic acids (such as penicillin, Pioneer adriamycin) in renal tubular secretion, the increase of antibiotic plasma concentration and the extension of time for their role. "

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