Basic Company Information
Company Advantage
Detail Company Introduction
Sulphoranphane and DNJ to sell
1. Sulphoranphane 1% 10% 20% 50%
Main functions:
◆ Anticancer activity of sulforaphane
◆ Antioxidant functions of sulforaphane: a potent inducer of phase II detoxication enzymes
[Product name]: Sulphoraphane (SFN)
[Used part]: Broccoli seeds
[Chemical name]: 1-isothiocyanato-4-(methyl-sulfinyl) butane
[Structural formula]: C6H11S2NO
[Molecular weight]: 177.29
Abstract
A number of natural compounds with inhibitory effects on tumorigenesis have been identified from our diet. Several studies have documented the cancer-preventive activity of a significant number of isothiocyanates (ITCs), the majority of which occur in plants, especially in Cruciferous vegetables. The most characterized ITC is sulforaphane (SFN). SFN has received a great deal of attention because of its ability to simultaneously modulate multiple cellular targets involved in cancer developmentin cluding: (i) DNA protection by modulating carcinogen-metabolizing enzymes and blocking the action of mutagens; (ii) inhibition of cell proliferation and induction of apoptosis, thereby retarding or eliminating clonal expansion of initiated, transformed, and/or neoplastic cells; (iii) inhibition of neoangiogenesis, progression of benign tumors to malignant tumors, and metastasis formation. SFN is therefore able to prevent, delay, or reverse preneoplastic lesions, as well as to act on cancer cells as a therapeutic agent. Taking into account this evidence and its favorable toxicological profile, SFN can be viewed as a conceptually promising agent in cancer prevention and/or therapy.
2. DNJ
INCI NAME：1-DNJ
Function:
◆ Treatment of diabetes
◆ Inhibition of tumor metastasis
◆ Antiviral
◆ Relieve of cough
English name: 1-Deoxynojirimycin (DNJ)
Chemical name: 3, 4, 5- triatomic - 2- methylol four hydrogen pyridines
CAS Reg.：19130-96-2
Structural formula: C6H13NO4
Molecular weight: 163
Origin
The 1-Deoxynojirimycin (DNJ) was first obtained from the streptomycete by Inoue as an antibiotic. It’s to be known as two main origins: plant and microorganism．The plant includes: mulberry leaves and roots, Commelina communis, Adenophora triphylla var. japonia, Jacobinia suberecta, Hyacinthus orientalis，While, the microorganism originates including: Streptomyces LavendulaeGC-148 and Bacillus. Our company has already separated 6 kinds of DNJ from the mulberry leaf: 1-DNJ, N-Me-DNJ, GAL-DNJ, fagomine, DAB and Calystegin B2.
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