Spironolactone

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Spironolactone
Posting date : Feb 11, 2009
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CHEMICAL | Pharmaceut
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30-
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Spironolactone Molecular formula : C24H32O4S MW : 416.57 CAS No. 52-11-01-7 Nature : 198-207 ° C melting point (Dec.). Specific rotation -37 ° (c = 1, CHCl3). Water-soluble practically insoluble Packing:25kg/Drum Nature : alias antisterone. The white crystalline powder. A slight smell mercaptan. Stability in the air. The temperature of 203 ° C to 209. Do not dissolve in water, soluble in organic solvents. Inefficient diuretics. Aldosterone with a similar chemical structure. Mainly for the treatment of elevated aldosterone and the refractory edema. May acetylene-diol by Grignard reaction, carboxylation, salt, hydrogenated, lactones, oxidation, eliminate, Addition synthesis steps.
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