Griseofulvin

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Griseofulvin
Posting date : Jan 22, 2008
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Free Member Scince Jan 22, 2008
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30-
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Detailed Description
Systematic name (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H, 4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione Identifiers CAS number: 126-07-8 ATC code: D01AA08 D01BA01 PubChem: 441140 DrugBank: APRD01004 Chemical data Formula: C17H17ClO6 Mol. mass 352.766 g/mol Pharmacokinetic data Bioavailability Highly variable (25 to 70%) Metabolism Hepatic demethylation and glucuronidation Half life: 9-21 hours Therapeutic considerations Pregnancy cat. B3 (Au), C (U.S.) Legal status POM (UK), B-only (U.S.) Routes Oral

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