Mirogabalin (DS-5565) drug for sale

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Product
Mirogabalin (DS-5565) drug for sale
Posting date : May 08, 2018
Membership
Free Member Scince May 07, 2018
Min. Order Quantity
5
Supply Abillity
Yes
Port
75
Payment Terms
visa, mastercard, American express, bank transfer, bitcoin, litecoin, dash, zcash
Package
OEM
Keyword :
Category
Contact
Thomas Vendor
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Product Detail
Company Info
 
Quick Detail
Place of Origin
United States [US]
Brand Name
Mirogabalin
HS-CODE
30-
Package & Delivery Lead Time
Package
OEM
Detailed Description
The mechanism of the depressive effect of Mirogabalin (DS-5565) is associated with the inhibition of reverse neuronal seizure of catecholamines (norepinephrine, dopamine and serotonin) in the central nervous system. Mirogabalin is an antagonist of muscarinic cholinergic receptors in the central nervous system and periphery, and therefore, one of the most potent depressants in this regard. It also has antihistamine and anti-adrenergic properties.Effective concentrations of mirogabalin in the blood are on average, from 120 to 240 ng / ml. The concentrations of mirogabalin in tissues are higher than in plasma, where 92% is associated with blood plasma proteins. Metabolized in the liver, half-life from the plasma from 10 to 28 hours for mirogabalin. It is allocated, mainly, with urine. Complete excretion within 7 days. Mirogabalin penetrates the placental barrier, is determined in breast milk in concentrations similar to plasma.Mirogabalin in doses above 150 mg / day reduces the threshold of convulsive activity, therefore, one should consider the risk of seizures in patients with anamnesis, and in the category of patients who are predisposed to this because of age or trauma. Treatment miragabalinom in old age should be under careful physical control and with the use of minimal doses of the drug, increasing them gradually, in order to avoid the development of delirious disorders, hypomania and other complications. Patients with a depressive TIR phase can go into a manic stage.
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