Bulevirtide

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Selling leads
Bulevirtide
Posting date : Jun 29, 2026
Membership
Free Member Scince Jun 22, 2026
FOB Price
1
Min. Order Quantity
10g
Supply Abillity
50000kgs
Port
Beijing
Payment Terms
100% TT in Advance
Package
1
Keyword :
API
Category
Contact
Winnie Wang
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN Brand
Model Number
2012558-47-1
HS-CODE
-
Package & Delivery Lead Time
Package
1
Delivery Lead Time
7-14
Detailed Description
Bulevirtide (CAS: 2012558-47-1, also known as MyrB, Myrcludex B or Hepcludex) is a white to off-white solid peptide HBV/HDV entry inhibitor and NTCP blocker. Its full peptide sequence is {Myr}-Gly-Thr-Asn-Leu-Ser-Val-Pro-Asn-Pro-Leu-Gly-Phe-Phe-Pro-Asp-His-Gln-Leu-Asp-Pro-Ala-Phe-Gly-Ala-Asn-Ser-Asn-Asn-Pro-Asp-Trp-Asp-Phe-Asn-Pro-Asn-Lys-Asp-His-Trp-Pro-Glu-Ala-Asn-Lys-Val-Gly-NH₂.
As a first-in-class viral entry antagonist, it selectively blocks the sodium-taurocholate cotransporting polypeptide (NTCP) receptor on hepatocytes, preventing hepatitis B virus (HBV) and hepatitis delta virus (HDV) from binding and invading liver cells. Beyond viral entry blockade, it further suppresses HBV covalently closed circular DNA (cccDNA) transcriptional activity and lowers HBcrAg levels after sustained administration. Clinically proven safe and efficacious, it serves as a novel therapeutic option for compensated chronic hepatitis delta patients; long-term 3-year treatment achieves HDV clearance in cirrhotic patients, while it is not indicated for decompensated liver disease cases. This high-purity reagent-grade peptide is widely supplied for pharmaceutical research, virology laboratory studies, preclinical development and mechanism exploration of chronic hepatitis B and D co-infection.

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