5-APB

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5-APB
Posting date : Jun 30, 2014
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Free Member Scince Jun 19, 2014
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30-
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5-(2-aminopropyl)benzofuran or 1-benzofuran-5-ylpropan-2-amine (5-APB) is a triple monoamine reuptake inhibitor with Ki values of 180, 265 and 811 for NET, DAT and SERT respectively as well as being a potent agonistfor the 5-HT2B receptor (Ki 14nM).This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA. The subjective effects andstructure-activity relationship suggest that 5-APB is also a monoamine releasing agent. 5-APB is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by mass and doses should be adjusted accordingly. 5-APB is also an agonist of the 5-HT2C receptor as well as a triple monoamine reuptake inhibitor.It has been sold as a designer drug since 2010. Anecdotal reports from users suggest it has stimulant and empathogeniceffects, but less psychedelic action than related compounds such as 6-APB and 5-APDB. --------------------- Email: Emily@cwtbiotech.com Skype: emily.feng9

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