Paclitaxel  

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Paclitaxel  
Posting date : Feb 28, 2013
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29-
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Paclitaxel   EINECS:205-285-7  Molecular Formula:C47H51NO14  CAS Registry Number:33069-62-4  Molecular Weight:853.92  Density:1.39g/cm3  Water solubility:solubile in methanol: 50 mg/mL,clear,colorless  Boiling Point:957.115 °C at 760 mmHg  Melting Point:213-216℃Flash Point:532.644 °C  Storage Temperature:2-8°C  Refractive index:-49 °(C=1,MeOH)  Solubility:solubile in methanol: 50 mg/mL,clear,colorless  Biological Activity:Antitumor agent; promotes and stabilizes tubulin polymerization,causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells,triggering apoptosis.  Appearance:White Powder  Stability:Stable. Incompatible with strong oxidizing agents. Combustible.  Usage:  An antineoplastic. Used in the study of structure and function of microtubles into tubulin 

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