Colchicine 　

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Colchicine 　 EINECS:200-598-5　 Molecular Formula:C22H25NO6　 CAS Registry Number:64-86-8　 Molecular Weight:399.44　 Density:1.32 g/cm3　 Water solubility:45 g/L (20℃)　 Boiling Point:RELATIVE DENSITY　 Melting Point:150-160℃Flash Point:392.9°C　 Alpha:-250 o (C=1,ALCOHOL)　 Storage Temperature:Poison room　 Refractive index:1.584　 Solubility:　 Biological Activity:Plant-derived alkaloid that binds to tubulin and depolymerizes microtubules.　 Appearance:yellow powder　 Stability:Stable. Light sensitive. Incompatible with strong oxidizing agents.　 Usage:　 An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signal　

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