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HS-CODE
S01-
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Detailed Description
Gymnema Silvestre Extract
Product Specifications: 25%, 75% Gymnemic Acid
Latin Name: Gymnema sylvestre .L
CAS: 90045-47-9
Part of Plant Used: Stem & Leaf
Appearance: Light Brown Powder
Extract Method: Grain Alcohol
Background:
People use Gymnema, a woody, climbing plant, as a remedy for snake bite wound for a long history, Gymnema leaves is too a kind of Chinese medicine. Its wide use in India is over 2000 years to treat honey urine. Because chewing the leaves can destroy the wet taste, people give it a common name, sugar destroyer. The medicinally active parts of the plant are the leaves and the roots. Recent clinical trials conducted in India have shown that an extract of Gymnema Sylvester is useful for controlling Blood Sugar.
Active Ingredients:
The active ingredients which have been identified as glycosides, several gymnemic acids. Gymnemic acids (GA) include GA, I, II, III and IV, are anti-sweet substance by experiments. Gurmarin, another constituent of the leaves, and gymnemic acid have been shown to block sweet taste in humans. Some researchers have suggested gymnemic acid as one possible candidate responsible for antidiabetic activity. Gymnemic acids inhibited glucan formation by streptococcus mutans in vivo and also markedly inhibited the activity of glucosyltransferase from bacterial coat. ecreasing capillary fragility.
Functions:
1. Gymnema sylvestre is a stomachic, diuretic, refrigerant, astringent, and tonic.
2. It has been found to increase urine output and reduce hyperglycemia in both animal and human studies.
3. Gymnemic acids are too useful for prevention of the formation of dental plaque and caries.
4. Gymnema's antidiabetic activity appears to be due to a combination of mechanisms.
5. Gymnema increases the activity of enzymes responsible for glucose uptake and utilization, and inhibits peripheral utilization of glucose by somatotrophin and corticotrophin.
6. Plant extracts have also been found to inhibit epinephrine-induced hyperglycemia.
Dosage:
The typical therapeutic dose of an extract, standardized to contain 24-percent gymnemic acids, is 400-600 mg daily. It is not clear from examining the studies whether divided doses are ideal but, because it is being used to regulate blood sugar, three divided doses with meals would seem ideal.
Safety:
No significant adverse effects have been reported, aside from the expected hypoglycemia. Safety in pregnancy has not been established.
Packing Detail:
Pack in paper-drums and two plastic-bags inside. Net Weight: 25kgs/drum.
Storage Situation:
Stored in a well-closed container and kept away from moisture and light.
Shelf Life:
two years under well Storage situation and stored away from direct sun light.
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