Progesterone

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Progesterone
Posting date : Aug 23, 2011
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Progesterone Product Name: progesterone English Name: Progesterone CAS number: 57-83-0 Packaging specifications: 1kg Specifications: 99%, pharmaceutical grade Product description: Progesterone -- Progesterone Name: 57-83-0 CAS # progesterone Chemical name: pregn-4-ene-3, 20-dione Molecular formula: C21H30O2 Appearance: white or almost white crystalline powder Quality standards: USP Progesterone is produced by the corpus luteum secretes a natural progesterone, estrogen in vivo to stimulate the endometrium has significant morphological effects, In order to maintain pregnancy required. Its pharmacological effects are mainly as follows: 1 during the menstrual cycle of late uterine mucosa glands growth, congestion uterus, endometrial thickening, Fertilized egg implantation ready. The fertilized egg implantation after to arise from the placenta, and reduce the gravid uterus excitability, inhibition of its activity, so that the fetus growth. The interaction with estrogen, promotes breast full development, prepare for milk. The uterine neck closed reduction, mucus thickening, make spermatozoon penetrates not easily; in large doses of hypothalamus by negative feedback effect, Suppression of pituitary gonadotropin secretion, resulting in suppression of ovulation in mice. This oral administration after 1 ~ 3 hours blood concentration peak, Due to the rapid metabolism and inactivation, the commonly used injection administration, but the sublingual or vaginal, rectal administration is also effective. Vaginal mucosa is rapidly absorbed, after 2 ~ 6 hours blood concentration peak. The main clinical for habitual abortion, dysmenorrhea, Menorrhagia or metrorrhagia, amenorrhea. Oral administration of large dose of progesterone deficiency disorders are also used, such as premenstrual syndrome, Anovulatory menstrual disorders, caused by benign breast disease, premenopausal and menopausal etc.. Vaginal delivery may substitute for oral, particularly for patients with liver disease

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