Eleven acid testosterone

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Eleven acid testosterone
Posting date : Aug 23, 2011
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Eleven acid testosterone Product Name: * eleven acid testosterone * English Name: Testosterone Undecanoate * CAS: 5949-44-0 * packaging specifications: 1kg * specifications : 97% ~ 103%, pharmaceutical grade Product description: Eleven acid testosterone Pinyin Name: Shiyisuan Gaotong English Name: Testosterone Undecanoate C30H48O3 456.71 This product is 17 beta hydroxy androst 4 ene - 3 - ketone eleven phas. According to the calculation of dry goods, including C30H48O3 should be 97% to 103%. [ character ] this product is white crystal or crystalline powder; odorless. The goods in the chloroform or benzene is easily dissolved in ethanol, dissolved in vegetable oil, slightly soluble in water, insoluble. The melting point of the product melting point ( Annex VI C ) ranged from 60 to 63 DEG c.. The specific rotation of the product, precision that will add two oxygen, six ring dissolved and diluted into quantitative 1ml each containing 14mg solution Liquid, according to the determination of ( Annex VI E ), specific rotation for 68 degrees to 72 degrees. Discrimination [ ] (1 ) the product of about 5mg, adding sulfuric acid to ethanol ( 2: 1) 1ml dissolved, namely yellow with green Fluorescent color. ( 2 ) for content determination of solution, as spectrophotometric method determination ( Appendix IV A ), in the 240nm wavelength Maximum absorption. ( 3) the goods should be infrared light absorption pattern and reference map ( spectral set 584) consistent. [ check ] other steroidal by high-performance liquid chromatography ( Appendix V D ) determination. Chromatographic condition and system suitability test with eighteen alkyl silane bonded silica as filler; acetonitrile isopropanol Water ( 40 : 40: 20) as mobile phase; the detection wavelength was 240nm. Number of theoretical plates by eleven acid testosterone peaks calculation should not be less than 2000. Method for the determination of the product, with the mobile phase respectively, each made of 1ml containing 2mg of test solution and 1ml each containing 0.04mg Control solution. According to the chromatographic conditions were test, take control solution 20 u l injected into the liquid chromatograph, adjusting and testing the spirit Sensitivity, make the main component of chromatographic peak height for recorder 20% of full range; and the two kinds of solution of the 20 L respectively Sampling, recording chromatogram to principal component peak retention time 2 times, for the sample solution in the chromatogram peaks of impurities significantly, quantity of The impurity peak area and shall not be greater than that of the control solution, main component peak area ( 2%). Loss on drying the product, with phosphorus pentoxide as a desiccant, vacuum drying to constant weight loss, weight not over 0.5% ( Appendix L ). Determination of the content of [ ] take this amount of goods, accurately weighed, and absolute alcohol dissolving and quantitatively dilute each made of 1ml Containing about 10 u g solution, as spectrophotometric method ( Appendix A ), the 240nm wavelength determination of absorption, another Eleven acid testosterone control amount, determined by the same method, calculation, that is. [ category ] male hormone. [ storage ] shading, seal preservation. [ ] eleven formulations of testosterone undecanoate injection Key words: Eleven acid testosterone quotation, eleven acid testosterone production, eleven acid testosterone traits, eleven acid testosterone use

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