Tripterygium Wilfordii Extract

본문 바로가기


Home > Product > Tripterygium Wilfordii Extract
Product
Tripterygium Wilfordii Extract
Posting date : Dec 22, 2011
Membership
Free Member Scince Sep 09, 2010
Keyword :
Category
Contact
          0 likes     
Product Detail
Company Info
 
Quick Detail
Place of Origin
HS-CODE
29-
Package & Delivery Lead Time
Detailed Description
We, Yongzhou Yidong Biotechnology Co.,Ltd. can supply can supply the Tripterygium Wilfordii Extract with the following specification: Triptolide 99% Min (HPLC) Celastrol 10-98% Min (HPLC) Wilforlide A 98% Min (HPLC) Demethylzeylasteral 98% Min (HPLC) Pristimerin 98% Min (HPLC) 3-methoxy-Celastrol 98% Min (HPLC) 3-methoxy-Pristimerin 98% Min (HPLC) If you are interested in this products, just contact us. Celastrol is a potent anti-inflammatory that is extracted from the root bark of the Chinese Thunder of God vine (Tripterygium wilfordii Hook) an ivy-like vine in China. Celastrol was used for years as a natural remedy for inflammatory conditions. It may be useful to minimize inflammation in Alzheimer’s disease (AD). Celastrol is a powerful antioxidant, in an isolated rat liver assay of lipidperoxidation, celastrol had a 50% inhibitory cocentration of 7 M, equivalent to about 15 times the antioxidant potency of a-tocopherol. Scientists have found it to be quite intensely immunosuppressive as well as anti-inflammatory. Celastrol inhibits macrophage activation, MHC I and II processing, TNF-alpha, IL1, IL2, and IL6, it may be developed to be a new anti rheumatoid arthritis(RA) drug. Triptolide, a diterpene triepoxide, is a purified compound from Tripterygium wilfordii hook F that has been identified as one of the major components responsible for the immunosuppressive and anti-inflammatory effects of this herb. It exists in the extracts of Chinese herb Tripterygium wilfordii hook F, which have been used for more than two centuries in traditional Chinese medicine to treat a variety of autoimmune and inflammatory diseases including rheumatoid arthritis. Recent explorations of the mechanisms of action of triptolide revealed many properties relevant not only to anti-inflammatory activity but also to anticancer activity. Antiproliferative and proapoptotic activity of triptolide has been shown with many different types of cancer cells in vitro and in vivo As an immunosuppressive agent with anti-inflammatory and anti-tumor properties, it is more effective in preventing T cell proliferation and interferon-g production than FK506. It induces apoptosis in T cells by activating DEVD cleaving caspases, blocks TNF-amediated induction of c-IAP1 and c-IAP2 and NF-kB activation. Triptolide also potentiates the activities of other agents and therefore may be useful not only as a single compound but also in combination with other cytotoxic drugs for cancer treatment. Its succinate salt water-soluble that is converted to triptolide in the serum, has recently been approved for Phase I clinical trials. ATTN: Robert Ai Mob: +86-18974697562 TEL: 86-746-4216222 FAX: 86-746-4216111 EMAIL: naturalextract@163.com MSN: naturalextract@hotmail.com http://www.yzyidong.com/en/gsjj.asp Yongzhou Yidong Biotechnology Co.,Ltd.

ECROBOT CO., Ltd, Business Registration Number : 220-88-71747, CEO J.W.Park, TEL : +82-2-552-7676, E-mail : E-mail : Contact us
Address : (Hwanghwa B/D 11F, Yeoksam-dong)320, Gangnam-daero, Gangnam-gu, Seoul, South Korea
About Us Privacy Policy Terms of use Copyright © 2000-2024 ECROBOT.COM. All rights reserved.
Top