Sinomenium Extract(jessica@organic-herb.com)

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Sinomenium Extract(jessica@organic-herb.com)
Posting date : Dec 17, 2009
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Sinomenium Extract Sinomenium Extract Sinomenium acutum(Thunb) Sinomenine HCl Product Specifications: C19H23NO4 MW: 329.4 CAS 115-53-7 MI 13: 8620 Long Term Storage: Product description:Sinomenine is an alkaloid isolated from the Chinese medicinal plant Sinomenium acutum. It has immunomodulating and anti-inflammatory activities [1-3]. Its anti-arthritic propery is related to the anti-proliferative effects on synovial fibroblasts [2] and lymphocytes [4]. Other anti-rheumatic mechanisms are attributed to its ability to decrease PGE2 and leukotriene C4 synthesis, and inhibit NO production [5]. Product Specific Literature References: [1] Impairment of macrophage eicosanoid and nitric oxide production by an alkaloid from Sinomenium acutum: L. Liu, et al.; Arzneimittelforschung 44, 1223 (1994) Abstract [2] Inhibition of lymphocyte proliferation by the anti-arthritic drug sinomenine: L. Liu, et al.; Int. J. Immunopharmacol. 16, 685 (1994) Abstract [3] Immunomodulatory effects of the alkaloid sinomenine in the high responder ACI-to-Lewis cardiac allograft model: D. Candinas, et al.; Transplantation 62, 1855 (1996) Abstract [4] Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine: L. Liu, et al.; Int. J. Immunopharmacol. 18, 529 (1996) Abstract [5] Synergistic effects of the alkaloid sinomenine in combination with the immunosuppressive drugs tacrolimus and mycophenolic acid: B. Vieregge, et al.; Planta Med. 65, 80 (1999) Abstract General Information: Formula picture - Datasheet Main Category: Immunomodulators Related Categories: / Inflammation Research > Other Reagents Inflammation / Natural Products If you have any further questions or need a sample ,please do not hesitate to contact with me. Wish you all of the best and regards! Sincerely yours, Ms.JessicaYang Sales Manager Organic Herb Inc. Phone:+86-731-82967870 Mobile:+86-158-74250704 Fax:+86 -731 -82967861 Email:jessica@organic-herb.com Skype:jessicayang22 MSN:yangfangsk@hotmail.com Website: http://www.organic-herb.com

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