Melatonin

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Melatonin
Posting date : Dec 23, 2010
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Melatonin Systematic (IUPAC) name N-[2-(5-methoxy-1H-indol-3-yl)ethyl] ethanamide Identifiers CAS number 73-31-4 ATC code N05CH01 PubChem 896 DrugBank APRD00742 ChemSpider 872 Chemical data Formula C13H16N2O2 Mol. mass 232.278 g/mol Therapeutic considerations Legal status Prescription Only (S4)(AU) POM(UK) OTC(US) Routes In humans: orally, as capsules, tablets or liquid, sublingually, or as transdermal patches. In lab animals: also injection. Melatonin is a hormone produced in the brain by the pineal gland from the amino acid tryptophan. The synthesis and release of melatonin are stimulated by darkness and suppressed by light, suggesting the involvement of melatonin in circadian rhythm and regulation of diverse body functions. Levels of melatonin in the blood are highest prior to bedtime. Synthetic melatonin supplements have been used for a variety of medical conditions, most notably for disorders related to sleep. Melatonin possesses antioxidant activity, and many of its proposed therapeutic or preventive uses are based on this property. New drugs that block the effects of melatonin are in development, such as BMS-214778 or luzindole, and may have uses in various disorders. Function: Improve sleep; Anti-aging; Adjust immunity function; Anti-cancer etc.

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