Carbomer934p

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Carbomer934p
Posting date : Dec 23, 2010
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Carbomer 934P / 974P Water Soluble Carbomer For Thickening, Suspending & Stabilizing Description CARBOMER range are synthetic high molecular weight crosslinked polymers of acrylic acid, which confirm to USP./INF. specifications as "CARBOMER" Use CARBOMER range, are water soluble polymer use to : Thicken To produce wide range of viscosities and flow properties. Suspend Insoluble ingredients. Stabilize & Emulsify Emulsions Grade & Applications Grades Solvent used in process Carbomer 934P / 974P (Benzene free) Benzene Cyclohexane & ethyl acetate Carbomer 934P / 974P - High purity oral pharmaceutical grade for formulations. ¤ Gel, Lotion and ointment. ¤ Oral liquid, suspension and emulsion. ¤ Sustained release formulation by matrix system. ¤ Opthalmic gel and eye - lotion. ¤ Transdermal (skin) drug delivery. ¤ Taste masking. Advantages Thickning efficiency High viscosities at low concentrations. Uniform performance Reproducibility unattainable with natural gums. Safety Years of successful use of carbomers. Temperature stability Extended up to 750C heating or cooling Unaffected by aging Excellent self life. Microbial resistance Resists bacterial attack and does not support mold growth Versatility Although primarily used in aqueous systems with neutralization. It can also be used in solvent systems, with or without neutralization. Elegance Smooth and luxurious feeling. Chilling Properties On refrigeration CARBOMER gel can retaining the cool temperature level for 48 hours to 72 hours. Low temperature necessary for vaccines, toxoids, insulin and human albumin can be store in pre-refrigerated CARBOMER gel, making it as a suitable medium for transporting these medicines. Specifications Appearance White fine free flowing powder. Odour Mild acidic. pH of 1% solution 2.5 to 3 Carboxylic content 56% to 68% Heavy metals Max. 2 ppm Temperature stability Up to 75°C Grades Grades Viscosity (20°C, 0.5% Neutralization) Carbomer 934P / 974P 29,400 - 39,400 cps. Preparation of Aqueous Transparent Gel D.M. water 97.0 gm. Carbomer (Any Grade) 0.5 gm. Sodium Hyroxide (10% solution) 2.5 gm. Neutralizers Recommended Sodium Hydroxide Potassium Hydroxide Triethanol Amine Triethyl amine, other alkalies etc.. Toxicity CARBOMER is a high molecular weight polymer. It is not absorbed by body tissues and is totally safe for human oral consumption. Test for toxicological tolerance show that it does not have pronounced physiological action and is non toxic. Storage Store in cool dry place. Keep away from moisture and water. Packing 5 kg., 20 kg., net in corrugated box. Certificate of Analysis ( CARBOMER - 974P ) No. Test Specification Results 1 Description White Free Flowing Powder White Free Flowing Powder 2 Solubility Complies Alkali Water 3 Identification A. Complies B. Complies Complies 4 Viscosity (0.5% Solution) Bet'n 29400 To 39400 Cps 36200 Cps 5 Loss on Drying NMT 2.0% 1.2% 6 Heavy Metals NMT 0.002% Complies 7 Assay For Carboxylic Acid Content Bet'n 56.0% To 68.0% 59.8% Certificate of Analysis ( CARBOMER - 934P ) No. Test Specification Results 1 Description White Free Flowing Powder White Free Flowing Powder 2 Solubility Complies Alkali Water 3 Identification A. Complies B. Complies Complies 4 Viscosity (0.5% Solution) Bet'n 29400 To 39400 Cps 38850 Cps 5 Loss on Drying NMT 2.0% 0.9% 6 Heavy Metals NMT 0.002% Complies 7 Limit Of Benzene (By Gc) NMT 0.01% 0.0021% 8 Organic Volatile Impurities Complies Complies 9 Assay For Carboxylic Acid Content Bet'n 56.0% To 68.0% 59.9%

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