hyaluronic acid&sodium hyaluronate

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hyaluronic acid&sodium hyaluronate
Posting date : Sep 30, 2009
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Hyaluronic Acid (HA) is a mucopolysaccharide composed of repeat disaccharide units of N-acetylglucosamine and glucuronic acid. The commercial HA is commonly a sodium salt, called sodium hyaluronate. HA is widely found in the extracellular matrix of animal tissues and vitreous humor. Its main biological role is water retention and lubrication. HA is a natural biotic component, widely existing in skin and any other tissue. It has outstanding moisture keeping ability, thus called Natural Moisturizing Factor (NMF) in the world. It is the best component used in cosmetics for moisture keeping in the nature. When HA applied to the skin, macromolecular HA can form an air permeable thin layer and keep the skin smooth and moist, and protect the skin from bacteria, dust, and ultraviolet ray. With low molecular HA penetrating into corium, it will slightly enlarge blood capillaries, speed circulation of blood, improve intermediary metabolism and nourishment absorbing ability of skin, thus eliminating wrinkles, increasing skin's elasticity and delaying its aging. HA as well can further hyperplasia of epidermis cell, clean oxygen free radical, prevent and rehabilitate breach of skin. Its aqueous solution has very high viscosity which can make water become thicker. Creams made by means of emulsifying HA with oil is fine and homogeneous with stable emulsification. HA is the best natural moisturizing component used in cosmetics. It has a good Compatibility and can be added in various cosmetics such as cream, lotion, cosmetic water, essence, milk for face washing, liquid for bath, agent for hair washing and protection, mousse, lip stick. The incorporated quantities are about 0.05%-0.5%. Test Items Specification Test Results Appearance White Powder White Powder Glucuronic Acid (%) ≥42.0 46.2 pH(0.1%Water Solution) 6.0-7.5 6.75 Molecular Weight (Da) 0.8-2.0×106 1.36×106 Protein,% <0.1 0.051 Loss on Drying ≤10.0 7.69 Residue on Ignition, % ≤20 15.35 Heavy Metalas Pb, ppm <20 <10 Arsenic,ppm <2 <2 Bacteria Count,CFU/g <100 <10 Hemolysis Negative Negative Viable Hemolytical Streptococci Negative Negative Other Indexes of Microorganism Accord with The National Standard Conclusion Complies

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