Allantoin

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Allantoin
Posting date : Jan 16, 2008
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29-
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Allantoin, the diureide of glyoxylic acid, is a crystallizable oxidation product of uric acid found in allantoic and amniotic fluids, in fetal urine and in many plants. (Ureide is a compound derived from urea and contains acid radicles. Those from one molecule of urea, as alloxan, are monoureides; those derived from two, as uric acid, are diureides). Allantoin is an urinary excretion product of purine metabolism in most mammals but not in higher apes including humans. It is produced synthetically by the oxidation of uric acid. Allantoin is active in skin-softening (keratolytic effect) and rapid cell regeneration by precipitating proteins on skin. Allantoin is used as an abrasive and astringent agent in the end products include cosmetic lotions, creams, suntan products, scalp preparations, shampoos , lipsticks and and various aerosol preparations. It is used in topical pharmaceutical preparations. Allantoin has been used in various oral hygeine preparations such as toothpaste and mouthwash as well as in eye drops to treat watering eyes and in ear drops to clean the ear canal.

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