Ginkgo Biloba Leaf Extract

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[Product Name] Ginkgo Biloba Leaf Extract [Latin Name] Ginkgo biloba L. [English Name] Ginkgo Biloba [Other Name] Maidenhair tree, Ginkgo Biloba [Origin & Technology] Ginkgo biloba is one of the world's oldest living tree species. The earliest record of the use of Ginkgo Biloba leaves as a medicine is mentioned in the Chinese Materia Medical Shen Nung Pen Tsao Ching, as an aid for blood circulation and disorders of lungs. They are also used for chilblains and as a wound plaster. In 1932, Japanese Furukawa isolated ginkgolides for the first time, which were further investigated for their chemical structure in 1966. Dr. Willmar Schwabe Company produced the first extract from leaves in 1965. With the advent and popularization of antioxidant theory in recent years, Ginkgo biloba has rapidly become one of the most widely used health supplements in the world. [Appearance] Light yellow powder [Specification] 1,Ginkgo Bilboa Extract 24/6 Total Ginkgo flavone glycosides >24% Total terpene lactones >6% 2,Ginkgo Bilboa Extract 24/6 Total Ginkgo flavone glycosides:≥24% Total terpene lactones:≥6% Ginkgolic acid:<1ppm 3,Ginkgo Bilboa Extract 24/6 Total Ginkgo flavone glycosides: ≥24% Quercatin: kaemperol:0.8~1.65 Total terpene lactones: ≥6% Rutin:<3.5% Ginkgolic acid:<1ppm 4,Ginkgo Bilboa Extract 24/6 Total Ginkgo flavone glycosides: ≥24% Quercatin: kaemperol:0.8~1.65 Total terpene lactones: ≥6% Rutin:<3.5% 5,CP2005 Total Ginkgo flavone glycosides >24% Quercatin: kaemperol: 0.8~1.5 Total terpene lactones > 6% Ginkgolic acid <1ppm 6.Germany Standard Total Ginkgo Flavone Glycosides 22.0%-27% Total Terpene Lactones 5.0%-7.0% Bilobalides 2.6%-3.2% Ginkgolic acid :≤1.0PPM 7.Water-Soluble Ginkgo Biloba Extract 24/6 Water Solubility: 5g Ginkgo Biloba Extract will be dissolved completely in 100g water Total Ginkgo Flavone Glycosides >24.0% Total Terpene Lactones >6.0% Ginkgolic acid : ≤1.0PPM [Functions] The leaves are still used in Chinese medicine to treat memory loss, stomach pain, dysentery, high blood pressure and anxiety as well as other respiratory problems like asthma, bronchitis, and poor circulation. The active component of Ginkgo biloba is the terpene fraction, which consists of ginkgolides and bilobalides. These ginkgo flavone-glycosides have powerful antioxidant and free radical scavenging capability. 1. Circulation Improvement: Ginkgo biloba extract increases circulation to both the brain and extremities of the body. One of the primary protective effects of the ginkgolides are their ability to inhibit a substance known as platelet-activating factor (PAF). PAF is a mediator released from cells that causes platelets to aggregate (clump together). High amounts of PAF are associated with damage to nerve cells, poor blood flow to the central nervous system, inflammatory conditions, and bronchial constrictions. Much like free radicals, higher PAF levels are also associated with aging. Ginkgolides and bilobalide protect nerve cells in the central nervous system from damage during periods of ischemia (lack of oxygen to tissues in the body). This effect may be supportive for persons who have suffered a stroke. In addition to inhibiting platelet stickiness, ginkgo biloba extract regulates the tone and elasticity of blood vessels. In other words, it makes circulation more efficient. This improvement in circulation efficiency extends to both large vessels (arteries) and smaller vessels (capillaries) in the circulatory system. 2. Antioxidant Properties: Ginkgo biloba extract may have antioxidant properties in the brain, retina of the eye, and the cardiovascular system. Its antioxidant activity in the brain and central nervous system may help prevent age-related declines in brain function. Ginkgo biloba extract for antioxidant activity in the brain is of particular interest. The brain and central nervous system are particularly susceptible to free radical attack. Free radical damage in the brain is widely accepted as being a contributing factor in many disorders associated with aging, including Alzheimer's disease. 3. Anti-Aging Properties Ginkgo increases blood flow to the brain and has excellent restorative effects on the nervous system. Hundreds of scientific studies, involving tens of thousands of patients, attest to the effectiveness of Ginkgo biloba extract for the many problems associated with cerebral vascular insufficiency and impaired mental performance in elderly patients. Ginkgo is of benefit for many of the presumed symptoms of aging such as: Anxiety and depression Memory impairment Poor concentration, decreased alertness Diminished intellectual capacity Vertigo, headache Tinnitus (ringing in the ears) Macular degeneration ( the most common cause of blindness in adults) Inner ear disturbances (which can cause partial deafness) Poor circulation in the extremities Impotence due to impaired penile blood flow 4. Dementia, Alzheimer's Disease and Memory Improvement Researchers recently reviewed all of the high-quality published studies on ginkgo and mild memory impairment, and concluded that ginkgo was significantly more effective than placebo in enhancing memory and cognitive function. Ginkgo is widely used in Europe for treating dementia. The reason that ginkgo is thought to be helpful for preventing or treating these brain disorders is because it improves blood flow in the brain and because of its antioxidant properties. Although many of the clinical trials have been scientifically flawed, the evidence that ginkgo may improve thinking, learning, and memory in people with Alzheimer's disease (AD) has been highly promising. Clinical studies suggest that ginkgo provides the following benefits for people with AD: Improvement in thinking, learning, and memory Improvement in activities of daily living Improvement in social behavior Fewer feelings of depression 5. PMS Symptoms One double-blind placebo-controlled study evaluated the benefits of Ginkgo biloba extract for women with PMS symptoms. This trial enrolled 143 women, 18 to 45 years of age, and followed them for two menstrual cycles. Each woman received either the ginkgo extract (80 mg twice daily) or placebo on day 16 of the first cycle. Treatment was continued until day 5 of the next cycle, and resumed again on day 16 of that cycle. The results were impressive. As compared to placebo, ginkgo significantly relieved major symptoms of PMS, especially breast pain and emotional disturbance. 6. Sexual Dysfunction Although there is no double-blind evidence at the time of this writing, case reports and open studies suggest that ginkgo can reverse the sexual dysfunction caused by drugs in the Prozac family as well as other types of antidepressant medications. 7. Eye problems The flavonoids found in ginkgo may help halt or lessen some retinal problems. Retinal damage has a number of potential causes, including diabetes and macular degeneration. Macular degeneration (often called age-related macular degeneration or ARMD) is a progressive, degenerative eye disease that tends to affect older adults and is the number one cause of blindness in the United States. Studies suggest that gingko may help preserve vision in those with ARMD. [Chemical Composition] The medical benefits of ginkgo biloba extract (GBE) rely on the proper balance of two groups of active components: the ginkgo flavone glycosides and the terpene lactones. The 24% ginkgo flavone glycoside designation on GBE labels indicates the carefully measured balance of bioflavonoids. These bioflavonoids are primarily responsible for GBE's antioxidant activity and ability to inhibit platelet aggregation (stickiness). These two actions may help GBE prevent circulatory diseases, such as atherosclerosis, and support the brain and central nervous system. The unique terpene lactone components found in GBE, known as ginkgolides and bilobalide, increase circulation to the brain and other parts of the body as well as exert a protective effect on nerve cells. Ginkgolides may improve circulation and inhibit platelet-activating factor (PAF). Bilobalide protects the cells of the nervous system. Recent animal studies indicate that bilobalide may help regenerate damaged nerve cells. [Dose] Many people take 120-160 mg of GBE, standardized to contain 6% terpene lactones and 24% flavone glycosides, two to three times per day. Amounts up to 240 mg per day are used by some people with cerebrovascular insufficiency, confusion and memory loss, and resistant depression. GBE may need to be taken for six to eight weeks before desired effects are noticed. Ginkgo may also be taken as a tincture of 0.5 ml three times daily.

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Ningbo Sino-Taipio Herbal Science Co.,Ltd.

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