Scutellaria Baicalensis Extract

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Scutellaria Baicalensis Extract
Posting date : Jan 15, 2008
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[Product Name] Scutellaria Baicalensis Extract [Latin Name] Scutellaria baicalensis Georgi [English Name] Baikal Skullcap Root [Other Name] S.amoena C.H. Wright (in Southern part) of China [Origin & Technology] Baikal or Chinese scullcap (Scutellaria baicalensis) is different from a related plant called American scullcap (Scutellaria laterifolia). Baikal scullcap was among seven ingredients in a combination oral herbal product known as PC-SPES that was used to treat prostate cancer. The U.S. Food and Drug Administration (FDA) initiated a nationwide recall of all PC-SPES in 2002 because the capsules were found to contain varying amounts of prescription drugs. Other combination formulas containing Baikal scullcap are used in Asian medicine to improve impaired brain function and to treat headaches. Baicalin, one chemical found in Baikal scullcap, is known to be anti-inflammatory. It is also antifungal, particularly for Candida, and it also seems to have antiviral properties; including possible effectiveness against HIV, the virus that causes AIDS. In animal studies, Baikal scullcap also has shown some effectiveness against diabetes and high blood pressure, but none of these effects has been studied in humans. [Appearance] Light Cream Yellow Powder [Specification] Baicalin 80%HPLC, 85% HPLC, 90%HPLC [Functions] Medical Function: 1. effects on digestive system: alcohol extract of huang qin or its ingredient baicalin can promote secretion of bile but another ingredient wogonin does not have this effect. Baicalein can promote movements of extra body intestines of rabbits but wogonin does not have this effect. Huang qin possesses a mild diarrhea effect. 2. anti - histamine effect: alkaloids of huang qin possesses antihistamine effect. It can inhibit edema of rats caused by carrageenin. 3. anti allergenic effect: alcohol extract of huang qin inhibits acute asthma attack and allergenic eczema. Baicalein has anti-toxin effect, inhibits permeability of capillaries and anti acetylcholine and anti anaphylaxis effects. 4. broad spectrum antibiotic effect 5. prevents atherosclerosis 6. blood thinning effect: one of the ingredients, Oroxylin A, can promote an enzyme to produce nitrogen oxide, a potential for stroke and myocardiac infarction therapy. 7. anti hepatitis B virus [Chemical Composition] 0~25.2%baicalin, baicalein, wogonin ( 4H – 1 – Benzopyran – 4 - one, 5,7 – dihydroxy – 8 – methoxy – 2 – phenyl – ( 632 – 85 - 9 ); C16H12O5, molecular weight 284.26; yellow needle crystal(ethanol solution or ethyl acetate - benzene), melting point 203°; easily soluble in methanol, ethanol, acetone and ethyl acetate; slightly soluble in benzene and water, not soluble in carbon bisulfide and petroleum ether), wogonoside (β-D-Glucopyranosiduronic acid, 5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl ( 51059-44-0) ), neobaicalein, 7-methoxy-baicalein, 7-methoxy-norwogoin, skullcapflavone Ⅱ, oroxylin A, β-sitosterol, stigmasterol, campesterol, benzoic acid, baialinase The leaf contains scutellarin and baicalin. The root has been recently reported to contain 2′, 5, 8 – trihydroxy – 7 - methoxyflavone, 2′ , 5 , 8 – trihydroxy – 6 , 7 - dimethoxyflavone and 4′4, 5, 7 – trihydroxy - 6 - methoxyflavanone. [Secure Quality] Due to unpredictable effects on stomach function, individuals with stomach or spleen disorders should not take Baikal scullcap. Dividuals with diabetes should avoid using Baikal scullcap because it blocks an enzyme that breaks down starches in the intestines. As a result, sugars are absorbed more slowly and blood sugar levels do not fluctuate as much. Potentially hypoglycemia (blood sugar that is too low) could occur. Symptoms of low blood sugar may include shakiness, sweating, confusion, distorted speech, and loss of muscle control. If not corrected, low blood sugar can lead to unconsciousness and even death.

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