Lenacapavir intermediate LPB

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Product
Lenacapavir intermediate LPB
Posting date : Apr 28, 2026
Membership
Free Member Scince Dec 22, 2025
FOB Price
1
Min. Order Quantity
1kg
Supply Abillity
50000kg
Port
Beijing
Payment Terms
100% TT in Advance
Package
25kg/bags;10kg/bgs;1kg/bags
Keyword :
Category
Contact
Winnie Wang
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN Brand
Model Number
2189684-53-3
HS-CODE
-
Package & Delivery Lead Time
Package
25kg/bags;10kg/bgs;1kg/bags
Delivery Lead Time
7-14 workdays
Detailed Description
Product Name: 4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-indazol-3-amine
Synonyms: Lenacapavir Intermediate 1; 3-Amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazole-7-boronic acid pinacol ester
CAS No.: 2189684-53-3
Molecular Formula: C₁₅H₁₈BClF₃N₃O₂
Molecular Weight: 375.58 g/mol
Key Specifications:
  • Predicted Boiling Point: 462.5 ± 45.0 °C
  • Predicted Density: 1.39 ± 0.1 g/cm³
  • Predicted pKa: 2.00 ± 0.50
  • Appearance: Solid (typical)
  • Purity: ≥98% (determined by HPLC; full batch-specific COA provided)
  • Storage: Recommended to store at -20°C, protected from light and moisture
Product Overview:
This is a key early-stage intermediate in the synthesis of Lenacapavir (GS-6207), the novel HIV-1 capsid inhibitor. It features a boronic acid pinacol ester group, serving as a critical building block for the Suzuki coupling reactions in the API synthetic route.
Applications:
  • Early-stage intermediate for Lenacapavir (anti-HIV drug) manufacturing and process development
  • Used in synthetic route optimization, pilot scale-up, and manufacturing process validation
  • Applied in coupling reaction development and boronic acid chemistry studies
Additional Information:
  • Full analytical documentation (¹H NMR, LC-MS, elemental analysis) available upon request
  • Custom synthesis and bulk production quantities are available
  • For research and laboratory use only; not intended for direct human administration.

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