Lenacapavir intermediate LP-4

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Product
Lenacapavir intermediate LP-4
Posting date : Apr 28, 2026
Membership
Free Member Scince Dec 22, 2025
FOB Price
1
Min. Order Quantity
1kg
Supply Abillity
50000kg
Port
Beijing
Payment Terms
100% TT in Advance
Package
25kg/bags;10kg/bgs;1kg/bags
Keyword :
Category
Contact
Winnie Wang
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN Brand
Model Number
2189684-54-4
HS-CODE
-
Package & Delivery Lead Time
Package
25kg/bags;10kg/bgs;1kg/bags
Delivery Lead Time
7-14 workdays
Detailed Description
Product Name: tert-Butyl (S)-(1-(3-bromo-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)carbamate
Synonyms: Lenacapavir Intermediate 2; GS-6207 Intermediate
CAS No.: 2189684-54-4
Molecular Formula: C₂₄H₂₇BrF₂N₂O₄S
Molecular Weight: 557.45 g/mol
Key Specifications:
  • Predicted Boiling Point: 636.8 ± 55.0 °C
  • Predicted Density: 1.42 ± 0.1 g/cm³
  • Predicted pKa: 10.37 ± 0.46
  • Appearance: Solid (typical)
  • Purity: ≥98% (determined by HPLC; full batch-specific COA provided)
  • Storage: Recommended to store at -20°C, protected from light and moisture
Product Overview:
This is a key advanced chiral intermediate in the multi-step synthesis of Lenacapavir (GS-6207), the novel HIV-1 capsid inhibitor. It features a Boc-protected chiral amine with the butynyl-sulfonyl side chain, representing a critical coupling step in the API manufacturing route.
Applications:
  • Advanced intermediate for Lenacapavir (anti-HIV drug) manufacturing and process development
  • Used in synthetic route optimization, pilot scale-up, and manufacturing process validation
  • Applied in chiral synthesis and coupling reaction development
Additional Information:
  • Full analytical documentation (¹H NMR, LC-MS, chiral HPLC, elemental analysis) available upon request
  • Custom synthesis and bulk production quantities are available
  • For research and laboratory use only; not intended for direct human administration.

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