Orforglipron Intermediate N-3

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Product
Orforglipron Intermediate N-3
Posting date : Apr 27, 2026
Membership
Free Member Scince Apr 24, 2026
FOB Price
1
Min. Order Quantity
1kg
Supply Abillity
50000kg
Port
Beijing
Payment Terms
100% TT in Advance
Package
25kg/bags;10kg/bgs;1kg/bags
Keyword :
Category
Contact
Winnie Wang
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN Brand
Model Number
2212021-61-7
HS-CODE
-
Package & Delivery Lead Time
Package
25kg/bags;10kg/bgs;1kg/bags
Delivery Lead Time
7-14 workdays
Detailed Description
Product Name:
tert-Butyl (S)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-3-(2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
Synonyms:
Orforglipron Intermediate, Olagliflon Intermediate Impurity 13
CAS No.: 2212021-61-7
Molecular Formula: C₂₃H₂₈FN₅O₃
Molecular Weight: 441.5 g/mol

Key Specifications & Properties:
  • Appearance: White to off-white solid
  • Predicted Density: 1.32 ± 0.1 g/cm³
  • Predicted pKa: 11.51 ± 0.70
  • Stereochemistry: Single (S)-enantiomer, high chiral purity (≥98% ee typical)
  • Storage: Room temperature
  • Purity: ≥98% (determined by HPLC; full batch-specific COA provided)

Application & Use Case:
This compound is a critical synthetic intermediate and impurity reference standard for Orforglipron (Olagliflon), a novel oral GLP-1 receptor agonist under clinical development. It is widely used in:
  • Pharmaceutical process development and scale-up for GLP-1 drug candidates
  • Analytical method validation (HPLC, LC-MS, chiral chromatography)
  • Stability testing and forced degradation studies
  • Regulatory submissions (IND/ANDA/DMF) requiring intermediate and impurity characterization

Additional Information:
  • Full analytical documentation available: HPLC, chiral HPLC, ¹H NMR, ¹³C NMR, LC-MS, elemental analysis, and COA
  • Custom synthesis and bulk production quantities available upon request
  • For research and laboratory use only; not intended for human or veterinary therapeutic administration.

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