The CRISPR-Cas9 system is a prokaryotic immune system driven by RNA that triggers resistance to foreign genetic elements and provides a form of acquired immunity. sgRNA serves as a guide to recognize and combine target DNAs, allowing activated Cas9 nuclease to attach, cleave, and modify the PAM downstream target DNA. CRISPR-based genome editing technology has made it easier and faster than ever to alter specific DNA sequence in the genome or to perform genome-wide functional screening tests to identify genes involved in a particular phenotype. Thus, CRISPR-Cas9 is considered as the most promising tool in gene modification.
The sgRNA design center of Synbio Technologies provides services such as single CRISPR-Cas9 sgRNA plasmid or sgRNA library design, downstream verification, and stable cell line construction. We offer a one-stop solution for CRISPR-Cas9 projects to achieve high genome editing efficiency.
Synbio Technologies provides high-purity ready-to-use CRISPR-Cas9 sgRNA which can be directly injected or transcribed into cells for the following gene editing experiments.
Synbio Technologies can design and construct sgRNA vectors for a variety of different species meanwhile sgRNA vector construction service is fast and high-quality.
If you have any question, please contact us anytime for assistance in business days. Our experienced project managers will provide you professional support to ensure the success of your project.
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