BUY AICAR/Acadesine Sarms Powder Provide Sample package

English name:	AICAR
Alias:	Acadesine
CAS No.:	2627-69-2
Molecular formula:	C9H14N4O5
Molecular weight:	258.23
Purity:	>99%
Characters:	Kind of white solid powder.
Packing:	According to customer requirements
Shipping Method	By Fedex,DHL,TNT,EMS ect.

A number of examples will follow showing AICAR doses uses in research studies, results from treatment, and approximate human equivalent doses, assuming an about-200 lb (90 kg) human for illustration:

In “AMPK and PPARdelta agonists are exercise mimetics“:

Mice, of a strain which is genetically susceptible to obesity and diabetes, were administered AICAR at 500 mg/kg daily for 5 weeks. Their endurance capacity increased by 44%, and expression of 32 genes favorable to metabolism was increased.

Human equivalent dosing would be about 3.2 grams per day, or about 64 vials of product as commonly sold. An example cost of this many 50 mg vials (current as of 2014) would be about $1500.

In “AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats“:

Rats were injected subcutaneously once with AICAR at 250 mg/kg. Improvement in whole body insulin sensitivity both post-injection and at the 24 hour point was comparable to what occurs when a bout of exercise is performed rather than an AICAR injection being given.

Human equivalent dosing would, again, be about 3.2 grams per day.

In “The Full Capacity of AICAR to Reduce Obesity-Induced Inflammation and Insulin Resistance Requires Myeloid SIRT1“:

Both lean and diet-induced-obese mice were administered AICAR at 150 mg/kg daily for 5 weeks. For the lean mice AICAR provided no effect on fat mass or insulin sensitivity, but significant improvement did occur for the diet-induced-obese mice. (Interestingly, the improvement was shown to be associated with reduction of the inflammatory cytokines TNFα, IL-6, and MCP-1, and required the presence of SIRT1, just as an aside, but it helps make sense of the article title.)

Human equivalent dosing would be about 1 gram daily.

Other studies may be found, but dosings will be similar to the above.

Reputed Dosage in Elite Cycling

I do not myself have a direct example known to me personally, but reputedly typical dosage has been about 500 mg/day for about four weeks prior to an event. This is lower than human-equivalent from animal research studies, but not so much so as to strain credulity. (In contrast, for example only 50 mg per day instead of 500 mg absolutely does strain credulity, let alone the 10 mg doses used by some as part of their stacks.)

 

In general I would recommend against using AICAR, but if wishing to do so anyway, I would use 500 mg/day for a limited period of time such as 4 weeks. For almost all persons this would be financially impractical with 50 mg pre-prepared vials. If however able to obtain pure AICAR powder at, for example, $150 per gram and to prepare one’s own IV solutions, such an administration might cost “only” about $75/day.

The purpose would have to be improved endurance capacity; this would be a ridiculous amount to pay for fat loss benefit.

 

 

Sarms Products List:

Sarms Powder
62	YK11	1370003-76-1
63	SR9009	1379686-30-2
64	Andarine	401900-40-1
65	Rad140	1182367-47-0
66	Ostarine	841205-47-8
67	MK-677	159752-10-0
68	Lgd-4033	1165910-22-4
69	Gw501516	317318-70-0
70	Aicar	2627-69-2

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