NM-2201 NM2201 CBL2201 naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate

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NM-2201 NM2201 CBL2201 naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3...
Posting date : Jun 07, 2017
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Free Member Scince Jun 05, 2017
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Product Detail
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Place of Origin
China [CN]
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skype rosechemical
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email rose@overcomer-cn.com
HS-CODE
3824-90
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Detailed Description

 

 

Company Information

 

Overcomer Research Chemicals Co., Ltd is specialized in research chemicals. Our factory is located in Shanghai, China. Factoty has much production experience. And our export department was opened in year 2014.

Our company supply high quality products with the most competitive prices. If have any need or question, contact us freely. Hope we can have chance to build good long-term cooperation.

 

 

 

 

Product Detail

 

 

NM-2201 (also known as CBL-2201) is an indole-based synthetic cannabinoid that presumably has similar properties to the closely related 5F-PB-22 and NNE1, which are both full agonists and unselectively bind to CB1 and CB2receptors with low nanomolar affinity.

 

 

 

Pharmacology

NM-2201 acts as a full agonist with a binding affinity of 0.332nM at CB1 and 0.732nM at CB2 cannabinoidreceptors.

 

 

Chemical Data of NM-2201

Density: 1.2±0.1 g/cm3
Boiling Point: 565.2±30.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.5 mmHg at 25°C
Enthalpy of Vaporization: 84.9±3.0 kJ/mol
Flash Point: 295.6±24.6 °C
Index of Refraction: 1.592
Molar Refractivity: 109.0±0.5 cm3
#H bond acceptors: 3
#H bond donors: 0
#Freely Rotating Bonds: 8
#Rule of 5 Violations: 1

 

ACD/LogP: 6.49
ACD/LogD (pH 5.5): 5.75
ACD/BCF (pH 5.5): 13832.67
ACD/KOC (pH 5.5): 32036.73
ACD/LogD (pH 7.4): 5.75
ACD/BCF (pH 7.4): 13832.67
ACD/KOC (pH 7.4): 32036.73
Polar Surface Area: 31 Å2
Polarizability: 43.2±0.5 10-24cm3
Surface Tension: 42.2±7.0 dyne/cm
Molar Volume: 322.2±7.0 cm3

 

 

NM-2201 (also known as CBL-2201) is an indole-based synthetic cannabinoid that is presumably a full agonist and unselectively binds to CB1 and CB2 receptors with low nanomolar affinity. Little to no research data available on this chemical makes it impossible to describe it's properties in detail.

 

NM-2201 was discovered by Alexandros Makriyannis from Northeastern University. It has been told by users that this drug is the most potent chemical from these types of drugs. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.

 

Its official designation in the IUPAC system is defined naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate , and simple chemical formula of the substance is summed up as C24H22FNO2 , with the molecular weight determined to be 375.4 g/mol.

 

Solvents as ethanol,DMSO, dichloromethane and dimethylformamide purged with a inert gas.NM-2201 is sparingly soluble in aqueous solutions.To enhance aqueous solubilty, dilute the organic solvent solution into aqueous buffers or isotonic saline.If performing biological experiments,ensure the residual amount of organic solvent is insignificant, since organic solvents may have physiological effects on low concentrations. . It is not recommended storing the aqueous solution for more than one day.

 

 

Other products details are as below.

 

 

 

Name Replacement
Ethylone Dibutylone
Ethylone BK-EDBP 
a-pvp   4C-PVP
a-pvp   TH-PVP
a-pvp   4f-php
4-cmc    2-NMC 
4-cmc    4-CEC 
3-cmc 4-CPRC
EP Dimethylphenidate(DP)
ab-chminaca  mab-chminaca (MABC)
JWH/5F-PB22/FUB-PB22 5F-PCN 
AH-7921 U-47700
PB-22/ AM2201 FDU-PB-22
AB-FUBINACA ADB-FUBINACA
 SDB-006 5F-sdb005
AKB-48

FUB-AKB48

 

 

Superiority

1 Best service, high quality and reasonable price

2. It's customers' right to choose the package (EMS, DHL, FedEx, UPS);

3.It's customers' right to choose the packing way for his produccts from many recent effective packing ways

4.Specials are possible when client's order is big enough, including the discount policy;

5.Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time;

 

 

 

 

F.A.Q

1.How is the quality?

The qualities of most products are above 99% purity, same are 99.7% purity.

2.How is the package?

Aluminum foil bag or as customer's required.

3.How is the storage?

Keep in dry and cool place.

4.Do I need to pay extra for shipping cost?

No, our price includes the shipping cost already; you need not pay for any tax and others.

5.Can I order sample to test?

Yes, you are welcome to order sample before placing bulk order. We will send the sample directly to your door by courier.   

 

 

 

 

Welcome contact for cooperation.

 

 

ROSE@OVERCOMER-CN.COM

SKYPE:   ROSECHEMICAL


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