Mouse Anti-Human ICOSLG Antibody

Inducible costimulator-ligand (ICOS-L) is a protein that in humans is encoded by the ICOSLG gene and ICOSLG has also been designated as CD275. ICOS-L is a member of the B7 family of costimulatory ligandssharing 19–20% sequence identity with CD80 and CD86. Two splice variants of human ICOS-L have been described and designated hGL50 and B7-H2/B7RP-1/hLICOS. Both molecules have an identical extracellular domain but differ at the carboxyl-terminal end of their cytoplasmic regions. In humans, cell surface expression of ICOS-L has been described on B cells, dendritic cells, monocytes/macrophages, and T cells.

 https://www.creativebiolabs.net/Mouse-Anti-Human-ICOSLG-Antibody-22825.htm