Modafinil CAS 68693-11-8

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Modafinil CAS 68693-11-8
Posting date : Jul 29, 2016
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Modafinil,Alertec,Modavigil,Provigil CAS 68693-11-8 
Systematic (IUPAC) name:2-benzhydrylsulfinylethanamideClinical dataTrade names    Alertec, Modavigil, Modiodal, Provigil, ModalertAHFS/Drugs.com    monographMedlinePlus    a602016Licence data    US FDA:linkPregnancycategory    AU: B3US: C (Risk not ruled out)Legal status    AU: S4 (Prescription only)CA: Schedule FUK: POM (Prescription only)US: Schedule IVDependenceliability    Psychological: Very lowPhysical: NegligibleAddictionliability    Very low to lowRoutes ofadministration    OralPharmacokinetic dataBioavailability    Not determined due to the aqueous insolubilityProtein binding    62%Metabolism    Hepatic (primarily via amide hydrolysis;CYP1A2, CYP3A4, and CYP2B6)Biological half-life    15 hours (R-enantiomer),4 hours (S-enantiomer)Excretion    Urine (80%)IdentifiersCAS Number    68693-11-8 YesATC code    N06BA07PubChem    CID: 4236IUPHAR/BPS    7555DrugBank    DB00745 YesChemSpider    4088 YesUNII    R3UK8X3U3D YesKEGG    D01832 YesChEBI    CHEBI:31859 ChEMBL    CHEMBL1373 YesChemical dataFormula    C15H15NO2SMolecular mass    273.35 g/mol
Modafinil is a wakefulness-promoting agent (or eugeroic) used for treatment of disorders such as narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea.It has also seen widespread off-label use as a purported cognition-enhancing agent.In English-speaking countries it is sold under the brand names Alertec, Modavigil, and Provigil. In the United States modafinil is classified as a schedule IV controlled substance and restricted in availability and usage, due to concerns about possible addiction potential. In most other countries it is a prescription drug but not otherwise legally restricted.
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