Bivalirudin Trifluoroacetate | Global Trade leader ecrobot

Product

Bivalirudin Trifluoroacetate

Posting date : Jun 01, 2015

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Membership

Free Member Scince Jun 01, 2015

FOB Price

15 USD

Min. Order Quantity

10g

Supply Abillity

1 ton per month

Port

China

Payment Terms

Western union,Money Gram

Package

Disguised package

Keyword :

Bivalirudin Trifluor

Category

CHEMICAL | Pharmaceut

Contact

David Lu

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Product Detail

Company Info

Quick Detail

Place of Origin

China [CN]

Brand Name

Yuancheng

Model Number

cx05@yccreate.com

HS-CODE

30-

Package & Delivery Lead Time

Package

Disguised package

Delivery Lead Time

within 3 working days

Detailed Description

Detailed Product Description

98% Injectable Polypeptide Hormones Bivalirudin Trifluoroacetate CAS 128270-60-0 Bivalirudin For Inhibiting Thrombin-mediated Platelet Activation & Aggregation

Quick Details:

Bivalirudin Trifluoroacetate
Sequence:D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
Alias:126:PN:WO2004076484PAGE:31 claimed protein;Angiomax;BG 8967;Bivalirudin;Hirulog; Hirulog 1
Cas No.: 128270-60-0
Molecular Formula: C98H138N24O33
Molecular Weight: 2180.29
Purity (HPLC): 98.0%min.
Appearance: White Powder
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): >80.0%
Water Content (Karl Fischer): <8.0%
TrifluoroAcetate Content(HPIC): >12.0%
MS (ESI): Consistent
Mass Balance: 95.0~105.0%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8℃ preservation
Manufacturer :Hezhong
Usage : This product is mainly used for the prevention of vascular forming interventional therapy in the treatment of unstable angina, ischemic complications before and after.It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation.

Description:

Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).

Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.

Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials

Application:

Bivalirudin is indicated for use as an anticoagulant in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty (PTCA).

Bivalirudin with provisional use of glycoprotein IIb/IIIa inhibitor (GPI) is indicated for use as an anticoagulant in patients undergoing percutaneous coronary intervention (PCI).

Bivalirudin is indicated for patients with, or at risk of HIT/HITTS undergoing PCI.

Bivalirudin is intended for use with aspirin and has been studied only in patients receiving concomitant aspirin.

Specifications :

Product name	Bivalirudin Trifluoroacetate
Appearance	White Powder
Assay	98%min
Molecular formula	C98H138N24O33
Molecular weight	2180.29
Package	2mg/vial or as your request
Shipping	Fast and secure shipping by DHL,EMS,UPS,TNT, FedEx..
Shipping leading time	Within 12 hours after receiving the payment
Payment Terms	Western Union, Money Gram , T/T, PayPal
Price	Negotiable