Niraparib tosylate is the tosylate salt form of the poly (ADP-ribose) polymerase (PARP) inhibitor niraparib, used in the maintenance treatment of certain platinum-sensitive, recurrent cancers.
Sorafenib is an oral, small-molecule, multi-targeted tyrosine kinase inhibitor (TKI) and the first systemic agent shown to improve survival in advanced hepatocellular carcinoma (HCC).
Lenalidomide is an oral immunomodulatory drug (IMiD) derived from thalidomide, used in the treatment of multiple myeloma, myelodysplastic syndromes, and certain lymphomas.
Olaparib is an oral, first-in-class poly (ADP-ribose) polymerase (PARP) inhibitor used in the treatment of cancers with deficiencies in homologous recombination repair (HRR), particularly those harbor…
Abiraterone acetate is an oral prodrug of abiraterone, a selective and irreversible inhibitor of cytochrome P450 17A1 (CYP17A1), used in the treatment of metastatic castration-resistant prostate cance…
Axitinib is an oral, potent, and selective second-generation inhibitor of vascular endothelial growth factor receptors (VEGFRs), used in the treatment of advanced renal cell carcinoma (RCC).
Pazopanib is an oral, small-molecule, multi-targeted tyrosine kinase inhibitor (TKI) used in the treatment of advanced renal cell carcinoma and soft tissue sarcomas.
Elvitegravir is a once-daily, HIV-1 integrase strand transfer inhibitor (INSTI) that requires pharmacokinetic boosting (e.g., with cobicistat) and is used in combination antiretroviral therapy.
Etravirine is a second-generation, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination regimens for the treatment of multidrug-resistant HIV-1 infection.
Cobicistat is a pharmacoenhancer (booster) that selectively inhibits cytochrome P450 3A (CYP3A) enzymes, used to increase systemic exposure of co-administered antiretroviral drugs in HIV-1 therapy.
Bictegravir is a second-generation, unboosted, once-daily HIV-1 integrase strand transfer inhibitor (INSTI) used as a cornerstone component of modern, single-tablet antiretroviral regimens.
Darunavir is a second-generation, non-peptidic, human immunodeficiency virus (HIV) protease inhibitor (PI) used as a core component of combination antiretroviral therapy (cART) for HIV-1 infection.
Velpatasvir is a pangenotypic, oral, hepatitis C virus (HCV) NS5A inhibitor used in combination with sofosbuvir for the treatment of all major HCV genotypes.
Sofosbuvir is an oral, direct-acting antiviral (DAA) prodrug and a nucleotide analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, used across all HCV genotypes.
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