Paricalcitol

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Paricalcitol
Posting date : Feb 25, 2026
Membership
Free Member Scince Jul 07, 2025
FOB Price
$314.5
Min. Order Quantity
10g
Supply Abillity
Stock
Port
Ningbo
Payment Terms
T/T 100%
Package
1g,10g,20g,
Keyword :
chemical
Category
Contact
Lunar
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Jinlan
HS-CODE
-
Package & Delivery Lead Time
Package
1g,10g,20g,
Detailed Description
CAS No.：131918-61-1
Molecular Formula：C₂₇H₄₀O₃
Molecular Weight：412.61

Characteristic

  • Appearance：White to off-white crystalline powder
  • Solubility：Practically insoluble in water; soluble in ethanol, methanol, DMSO
  • Storage：Sealed, dry, protected from light, refrigerated

Pharmacological Category

Selective vitamin D receptor agonist
Antihyperparathyroid agent

Mechanism of Action

  • Activates vitamin D receptor (VDR)
  • Suppresses parathyroid hormone (PTH) synthesis and secretion
  • Reduces parathyroid hyperplasia
  • Lower risk of hypercalcemia & hyperphosphatemia vs calcitriol

Indications

  • Secondary hyperparathyroidism in patients with chronic kidney disease (CKD)
    • Dialysis-dependent patients
    • Non-dialysis CKD patients

Key Features

  • Selective VDR activation
  • Lower calcemic/phosphatemic effect
  • Effective PTH control
  • IV and oral formulations available

Main Adverse Reactions

  • Hypercalcemia
  • Hyperphosphatemia
  • Nausea, vomiting
  • Headache
  • Dizziness

Contraindications

  • Hypersensitivity to paricalcitol
  • Hypercalcemia
  • Evidence of vitamin D toxicity
  • Severe hyperphosphatemia
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