Linaclotide

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Selling leads
Linaclotide
Posting date : Feb 25, 2026
Membership
Free Member Scince Jul 07, 2025
FOB Price
$313.5
Min. Order Quantity
10g
Supply Abillity
Stock
Port
Ningbo
Payment Terms
T/T 100%
Package
1g,10g,20g,
Keyword :
chemical
Category
Contact
Lunar
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Jinlan
HS-CODE
-
Package & Delivery Lead Time
Package
1g,10g,20g,
Detailed Description
CAS No.：851198-29-2
Molecular Formula：C₅₉H₇₉N₁₅O₂₁S₆
Molecular Weight：1526.79

Characteristic

  • Appearance：White to off-white powder
  • Solubility：Practically insoluble in water; soluble in acidic solutions
  • Storage：Sealed, dry, protected from light

Pharmacological Category

Guanylate cyclase‑C (GC‑C) agonist
Laxative / gastrointestinal agent

Mechanism of Action

  • Activates intestinal guanylate cyclase‑C
  • Increases intracellular and extracellular cGMP
  • Enhances chloride and bicarbonate secretion into intestinal lumen
  • Accelerates transit; reduces visceral hypersensitivity

Indications

  • Irritable bowel syndrome with constipation (IBS‑C)
  • Chronic idiopathic constipation (CIC)

Key Features

  • Oral, minimal systemic absorption
  • Improves both constipation and abdominal pain/discomfort
  • Once-daily dosing

Main Adverse Reactions

  • Diarrhea (most common)
  • Abdominal pain, bloating
  • Flatulence

Contraindications

  • Hypersensitivity to linaclotide
  • Known or suspected mechanical gastrointestinal obstruction
  • Pediatric patients < 6 years (risk of serious dehydration)
 
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