CAS 401900-40-1 Popular Sarm Powder Andarine S4 Raw Powder Sarms Powder Gtx-007 Andarine S-4

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CAS 401900-40-1 Popular Sarm Powder Andarine S4 Raw Powder Sarms Powder Gtx-007 ...
Posting date : Mar 19, 2018
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CAS:401900-40-1MF:C19H18F3N3O6MW:441.357 g/molAppearance:white to pale yellow powderPurity: >99%Certification: ISO 9001Suitable for: AdultPacking:Foil bag or as requirmentsSolubility: DMSO / PEG
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Selective androgen receptor modulators or SARMs are a novel class of androgen receptor ligands. They are intended to have the same kind of effects as androgenic drugs like steroids but be much more selective in their action, allowing them to be used for many more clinical indications than the relatively limited legitimate uses that steroids are currently approved for.
 
S-4 is an experimental or investigation-stage proprietary SARM research chemical developed by GTx Inc for treatment of benign prostatic hypertrophy, muscle wasting, and osteoporosis. S-4 is considered a partial agonist of the androgen receptors in target tissue. S-4 has less pronounced anabolic and androgenic compared to other SARMs. In trials treating BPH induced in animal models, S-4 reduced prostate weight as effectively as finasteride and without producing any reduction in muscle mass or other side effects common with androgen receptor binding compounds. Gao et al suggest that by binding to androgen receptors, S-4 prevents DHT from binding and activating, but bypasses the expected anti-androgenic effects that would occur from occupying androgen receptors due to the fact that S-4 itself is a partial agonist of androgen receptors. S-4 has also been shown to prevent bone loss, reduce body fat, and improve muscle strength and body composition in orchidectomized and ovariectomized rats.
Application:Andarine (GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the non-steroidal androgen antagonist bicalutamide as a lead compound.In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.Selective androgen receptor modulators (SARMS) bind to the androgen receptor and demonstrate osteo (bone) and myo (muscular) anabolic activity.Binding and activation of the Androgen receptor alters the expression of genes and increases protein synthesis which ultimately builds muscle.SARMS such as S4 can cause muscle growth in the same manner as steroids, however unlike testosterone and other anabolic steroids, SARMS (as nonsteroidal agents) do not produce the growth effect on prostate and other secondary sexual organs.SARMS not only represent a new potential treatment option for a wide spectrum of conditions such as muscle wasting diseases (from age-related to AIDS or cancer-related), but they also have immense potential for muscle building for Bodybuilders, fitness and athletes.S-4 in particular binds to the androgen receptor in muscle and bone to a third of the affinity of Testosterone.Packing:Discreet packing ways as your requirement, 100% go through.Storage:Store in cool and dry area and keep away from direct sunlight.Advantage:1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.2. Quality can be promised. Hot sell to Worldwide.3. Payment Terms: T/T Bank Transfer, Western Union and MoneyGram Available.4. Free Sample available at any time.5. Tracking your order at any time. Inform your order's further new situation at any time.6. Package: Professional packing with professional materials. 

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