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If you have an upcoming medical or dental procedure, your healthcare provider may administer ketamine. This anesthetic is typically used for short-term procedures, as its effects last between 5 and 25 minutes. It works by producing a general state of anesthesia (loss of sensation and awareness) and pain relief. Possible "off-label" uses for ketamine include treating certain types of depression or migraine headaches.

Ketamine is injected intravenously (IV, or into a vein) or intramuscularly (IM, or into a muscle) in a healthcare setting, by healthcare providers who are trained in administering anesthetics.