DescriptionAbemaciclib is an oral, highly selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6).It induces cell-cycle arrest in G1 phase and inhibits proliferation in HR+/HER2- breast cance…
Approved Indications
HR-positive, HER2-negative advanced or metastatic breast cancer in combination with:
Aromatase inhibitors
Fulvestrant
Key Features
Potent and selective CDK4/6 inhibition
…
Approved Indications
HR-positive, HER2-negative advanced or metastatic breast cancer in combination with:
Aromatase inhibitors
Fulvestrant
Key Features
Potent and selective CDK4/6 inhibition
…
Momelotinib - English API InfoName: Momelotinib (CYT‑387)CAS: 1056634-68-4 (free base)Formula: C₂₃H₂₂N₆O₂Molecular Weight: 414.47Class: JAK1/JAK2/ACVR1 inhibitorDescriptionMomelotinib is an oral, pote…
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