Amfonelic acid (AFA; WIN 25,978) for sale

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Home > Product > Amfonelic acid (AFA; WIN 25,978) for sale
Product
Amfonelic acid (AFA; WIN 25,978) for sale
Posting date : May 08, 2018
Membership
Free Member Scince May 07, 2018
Min. Order Quantity
1
Supply Abillity
Yes
Port
250
Payment Terms
visa, mastercard, American express, bank transfer, bitcoin, litecoin, dash, zcash
Package
OEM
Keyword :
Category
Contact
Thomas Vendor
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Product Detail
Company Info
 
Quick Detail
Place of Origin
United States [US]
Brand Name
AFA
HS-CODE
30-
Package & Delivery Lead Time
Package
OEM
Detailed Description
Amfonelic acid (AFA; WIN 25,978) is a reversible inhibitor of cholinesterase, directly stimulates impulse conduction in the neuromuscular synapse and in the central nervous system (CNS) due to blockade of the potassium channels of the membrane. Strengthens the effect on the smooth muscles of not only acetylcholine, but also adrenaline, serotonin, histamine and oxytocin. Amfonelic acid has the following pharmacological effects: - improves and stimulates impulse in the nervous system and neuromuscular transmission; - improves conductivity in the peripheral nervous system, impaired due to injuries, inflammation, the effects of local anesthetics, certain antibiotics, potassium chloride, etc .; - increases the contractility of smooth muscle organs under the influence of agonists acetylcholine, adrenaline, serotonin, histamine and oxytocin receptors, with the exception of potassium chloride; - improves memory, inhibits the gradual development of dementia. Does not have teratogenic, embryotoxic, mutagenic, carcinogenic and immunotoxic effects. Does not affect the endocrine system.With subcutaneous and intramuscular injection quickly absorbed. The maximum concentration in the blood is reached after 25-30 minutes after administration. Binding to blood plasma proteins - 40-50%. The drug quickly enters the tissues. Metabolised in the liver. The drug is excreted through the kidneys (mainly by tubular secretion and only 1/3 by glomerular filtration) and extrarenally (through the gastrointestinal tract). The half-life of the drug Amfonelic acid with parenteral administration is 2-3 hours. After parenteral administration, 34.8% of the dose is excreted unchanged in the urine.
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