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Posting date : Nov 24, 2016
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LevonorgestrelCAS:797-63-7 Assay:99%  Molecular Formula:C21H28O2 Molecular Weight:312.45 Quality Standard: USPPacking:1kg/foil bag/tinAppearance: White or almost white crystalline powderUsage: Progesterone drug, used for irregular menstruation, functional uterine bleeding, endometriosis, etcPayment terms:Western union; Money gram; T/T; Paypal; Bitcoin
Usage And Synthesis Oral contraceptives, levonorgestrel, also known as D- norethindrone, left Kanok ketone, is currently the most widely used oral contraceptives, the racemic optically active part of norethindrone, the activity ratio norethindrone strong double dose can be reduced by half, adverse reactions are also reduced accordingly. Rapid oral absorption, 0.5 ~ 1h, reached the peak. t1 / 2 of 10 ~ 24h.Protein binding rate of 93% to 95%, bioavailability, mainly located in the liver, kidney, ovarian and uterine body's organs and tissues, and its metabolites, mainly in the form of glucuronide and sulfate salts from the urine and feces in vitro. And ethinyl estradiol combination as a short-acting oral contraceptives. Its dual photo and three photo adverse reactions less, closer to women's normal hormone secretion type. Women can be used for emergency contraception, namely failure (condom slippage or breakage, coitus out of control, rhythm miscalculation, etc.) in the same room of post-coital contraception measures unprotected intercourse or other contraceptive methods.  As the three weekly photo of reducing the product with about 40%, so the fewer adverse reactions. Levonorgestrel such as changes in dosage form can also be used a variety of long-acting contraceptives. Used as a short-acting oral contraceptives: from the first five days of menstruation to start taking the compound levonorgestrel tablets, a day, even for 22 days, without interruption, at bedtime. So the next menstruation after serving five days to continue the medication. May have nausea, vomiting, headache, breast swelling after serving, acne, weight gain, depression, lowered HDL, breakthrough bleeding, amenorrhea. Liver and kidney dysfunction, breast masses were hanged. Uterine fibroids, hypertension and liver and kidney disease history of caution. Not as a regular birth control pills, to be taken next reliable contraceptive measures premenstrual medication. Women who smoke should not take (due to complicated by cardiovascular disease). Product description: Levonorgestrel (or l-norgestrel or D-norgestrel) is a second generation progestin (synthetic progestogen) used as an active ingredient in some hormonal contraceptives, including combined oral contraceptive pills, progestogen only pills, emergency contraceptive pills, intrauterine systems, contraceptive implants, and hormone replacement therapy.It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system
Application: Oral contraceptionAt low doses, levonorgestrel is used in monophasic and triphasic formulations of combined oral contraceptive pills, with available monophasic doses ranging from 100-250 μ G, and triphasic doses of 50 μ G/75 μ G/125 μ G. At very low daily dose of 30 μ G, levonorgestrel is used in some progestogen only pill formulations. Emergency contraceptionLevonorgestrel is used in emergency contraceptive pills (ECPs), both in a combined Yuzpe regimen which includes estrogen, and as a levonorgestrel-only method. The levonorgestrel-only method uses levonorgestrel 1.5 mg (as a single dose or as two 0.75 mg doses 12 hours apart) taken within 3 days of unprotected sex, with one study indicating that beginning as late as 120 hours (5 days) after intercourse could be effective. Intrauterine systemLevonorgestrel is the active ingredient in the Mirena & Skyla (Jaydess) intrauterine system. Contraceptive implantsLevonorgestrel is the active ingredient in Norplant and Jadelle. Hormone replacement therapyLevenorgestrel is combined with 17-beta estradiol in the Climara Pro hormonal patch.
Levonorgestrel CAS:797-63-7 Assay:99% Molecular Formula:C21H28O2 Molecular Weight:312.45
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