Quick Details:
CAS No: 120511-73-1Molecular formula: C20h24o2Molecular weight: 293.37Appearance: White powderPurity: >98%
Specification:
Product Name |
Arimidex |
Chemical name |
α,α,α',α'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile |
CAS |
120511-73-1 |
Purity |
99% |
Melting Point |
81.0~84.0°C |
Packing |
foil bag or tin. |
Appearance |
off-white color crystalline powder |
Standard |
Enterprise Standard |
Storage |
Shading , confined preservation |
Usage |
Anti-estrogen |
Molecular Fomular |
C17H19N5 |
Molecular Weight |
293.37 |
Molecular Structure |
|
Description:
Arimidex is a true aromatase inhibitor which works by blocking the aromatase enzyme in the body, thus limiting theamount of estrogen buildup that takes place. This compound has obvious benefits to bodybuilders who use aromatizing steroids such as testosterone. These individuals might face estrogen related side effects such as water bloat and "gyno", but by taking GP Arimidex while on cycle, the chance of any of these sides are greatly reduced. Applications: In studies that have been done, Arimidex has been shown to reduce estrogen in the body by roughly 50%. This is a good balance for bodybuilders , because some estrogen is needed in order for the full anabolic benefits of the steroids being taken to be achieved. These results are typically the same with a dosage of .5 mg a day as they are with a dosage of 1 mg a day, meaning that in most cases, a half tablet a day will be sufficient for estrogen control throughout cycle. Arimidex will begin taking it the day they start their cycle, Arimidex will run it throughout the duration of steroid administration. Arimidex is also important to point out GP Anastrozole's ability to increase testosterone in the body. Some studies have shown that natural testosterone levels have increases as much as 60% after the use of this substance for 7 days. Because of this, bodybuilders find Arimidex extremely effective during PCT where as they are trying to elevate natural levels as much as possible in order to avoid a post cycle "crash". Although Arimidex does increase testosterone levels slightly in the body, it is more often used in conjunction with other steroids to lower estrogen in the body. Many anabolic steroids will convert, or aromatize, in the body into estrogen, which causes many of the unwanted side effects like bloating and acne. Arimidex is one of the best compounds to lower the aromatizing effect of steroids.Dosage:Most men will find 0.5mg every other day to be a good starting point while on cycle if it is needed for side-effect prevention with 1mg every other day generally being the most anyone will ever need for this purpose.The same dose can be applied in physique sport competition, most notably bodybuilding; it is very common for many bodybuilders to supplement with Arimidex for 12-16 weeks leading up to a competition at a dose of 1mg every other day.
COA:
Items |
Standard |
Results |
Description |
White crystalline powder |
Complies |
Solubility |
Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile |
Complies |
Total Impurity |
max.0.5% |
0.18% |
Total Unspecified Impurity |
max. 0.2% |
0.08% |
Individual unspecified impurlty |
max. 0.1% |
0.05% |
Related compound B |
max. 0.2% |
0.07% |
Related compound C |
max. 0.2% |
0.04% |
Related compound D |
max. 0.1% |
0.05% |
Related compound E |
max. 0.1% |
0.06% |
Limit of cyclohexane |
max. 0.08% |
ND |
Limit of ethylacetate |
max. 0.1% |
0.07% |
Melting point |
81.0~84.0ºC |
82.5~83.2ºC |
Water |
max. 0.3% |
0.21% |
Residue on ignition |
max. 0.1% |
0.07% |
Heavy Metals |
max.0.001% |
Complies |
Assay(HPLC) |
98.0%~102.0% |
99.8% |
Storage |
Cool and dry |
Conclusion |
It complies to USP32 . |
HPLC:
Usages:An aromatase inhibitor. Used as an antineoplastic raw materials.Potent selective triazole aromatase inhibitors, can inhibit the cytochrome P-450 aromatase enzyme which depends blocking the biosynthesis of estrogen, and estrogen to stimulate breast cancer cell growth factors. Treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy after menopause for women with advanced breast cancer.
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