Epitope Mapping by X-ray Crystallography

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Epitope Mapping by X-ray Crystallography
Posting date : Jul 11, 2017
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Bella Smith
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Place of Origin
United States [US]
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Creative Biolabs
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3002-10
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Detailed Description
The gold standard approach, also the most unambiguous method for epitope mapping, is X-ray co-crystallography. X-ray co-crystallography allows mapping of both linear and conformational epitopes. By co-crystallizing the monoclonal antibody with its respective antigen, the epitope can be defined immediately with high accuracy.
Staffed by dedicated scientists with combined expertise in antibody engineering and protein X-ray crystallography, Creative Biolabs have extensive experience in crystallizing antibody/antigen complexes and resolving their 3D structures. In particular, we are able to map the epitopes of a large variety of antibody forms, including intact IgG, Fab, scFv, F(ab')2, diabody, minibody, miniantibody, tandem scFv and single domain antibody as well as protein A scaffold.
Please refer to our website at Creative Biolabs for more information regarding resolving the structure of an antigen/antibody complex.More information, please visit the website: http://www.creative-biolabs.com/Epitope-mapping-by-X-ray-Crystallography.html

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