High quality Ace-031 peptides powder for muscle growth

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Selling leads
High quality Ace-031 peptides powder for muscle growth
Posting date : May 09, 2017
Membership
Free Member Scince Mar 06, 2017
FOB Price
USD10
Min. Order Quantity
10vials
Supply Abillity
10000kits
Port
shanghai
Payment Terms
MoneyGram,Western Union，T/T
Package
vials
Keyword :
Ace-031
Category
CHEMICAL | Inorganic chemic | Fluorine chlorin | Chlorine
Contact
ceia
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
demeikai
HS-CODE
2801-10
Package & Delivery Lead Time
Package
vials
Delivery Lead Time
7 dyas
Detailed Description
Ace-031 Basic Info.Product Name:Ace-031Unit Size:1mg/VialAppearance:Lyophilized PowderContent:99%Physical State:White PowderStorage:Below -18cSynonyms:Acvr2b, Activin Receptor Type IibExport Markets:GlobalUsage:Bodybuilding ;Myostatin Blockers Ace-031 Description:ACE-031 is intended for research purpose only. ACE-031 should not be used for human consumption, diagnostic, therapeutic procedures, agricultural and veterinary purposes. ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases. ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth. ACE-031 belongs to class of proteins of TGF-beta super family that regulate muscle growth.ACE-031 acts on the molecular switches of these molecules and promote muscle growth. In experimental studies, ACE-031 promotes muscle growth and inhibits ActRIIB receptor signaling. In pre-clinical studies, administration of ACE-031 for two weeks increased skeletal muscle density, decreased leptin levels, and increased adiponectin.  Ace-031 Application:Some bodybuilders use ACE-031 to promote muscle growth and to improve lean muscle. No serious adverse events were reported after ACE-031. Most of the common adverse events are mild and tolerable. The polypeptide contains 368 amino acid molecules, which forms a very large polypeptide complex. Muscle growth is regulated by the production of amino acids , and TGF beta protein super family is mainly the regulator as indicated earlier the on and off switch mechanism is essential for muscle production. When ActRIIB receptors interact with the GDF-8, it sends an on signal, which in turn promotes muscle growth.
Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids . 
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