Sodium Sulfate BP

Name: Anhydrous Sodium Sulfate BPAction and Use: Laxative.Content: 98.5 per cent to 101.0 per cent (dried substance).CharactersAppearance: White or almost white powder, hygroscopic.Solubility: Soluble in water.IdentificationA. It gives the reactions of sulphates.B. It gives the reactions of sodium.C. It complies with the test for loss on drying (see Tests).Appearance of Solution: Solution S is clear and colourless.Acidity or Alkalinity:To 10 ml of solution S add 0.1 ml of bromothymol blue solution R1 . Not more than 0.5 ml of 0.01M hydrochloric acid or 0.01M sodium hydroxide is required to change the colour of the indicator.Chlorides: Maximum  450 ppm.Calcium : Maximum 450 ppm, if intended for use in the manufacture of parenteral dosage forms.Iron:Maximum 90 ppm, if intended for use in the manufacture of parenteral dosage forms.Magnesium:Maximum 200 ppm, if intended for use in the manufacture of parenteral dosage forms. To 10 ml of solution S add 1 ml of glycerol (85 per cent), 0.15 ml of titan yellow solution, 0.25 ml of ammonium oxalate solution and 5 ml of dilute sodium hydroxide solution and shake. Any pink colour in the test solution is not more intense than that in a standard prepared at the same time in the same manner using a mixture of 5 ml of magnesium standard solution (10 ppm Mg) and 5 ml of water .Heavy Metals:Maximum  45  ppm.Loss On Drying